INT281933

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (YWHAZ) mitochondrion (YWHAZ) protein complex (YWHAZ)
cytoplasm (YWHAZ) cytosol (YWHAZ) signal transduction (YWHAZ)
YWHAZ (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 1 96.60 Very High Very High Very High
Inflammation 51 90.76 High High
ischemia 1 74.60 Quite High
cINOD 28 64.76 Quite High
corticosteroid 3 39.36 Quite Low
cOX1 1 9.28 Low Low
COX2 2 8.64 Low Low
diclofenac 45 5.00 Very Low Very Low Very Low
acular 41 5.00 Very Low Very Low Very Low
alcohol 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 44 90.76 High High
Injury 6 83.96 Quite High
Autoimmune Disease 1 77.20 Quite High
Hypersensitivity 1 75.92 Quite High
Cv Unclassified Under Development 1 74.60 Quite High
Ocular Hypertension 8 71.84 Quite High
Increased Venous Pressure Under Development 16 66.72 Quite High
Miosis 8 50.48 Quite High
Pre-eclampsia 33 5.00 Very Low Very Low Very Low
Cataract 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is mobilized by phospholipases, especially cytoplasmatic phospholipase A2, and is metabolized by constitutive cyclooxygenase (COX-1) and inducible COX-2 into prostaglandins and related compounds, by lipooxygenase into leukotrienes and by p450 into epoxieicosanoid acids[10].
Localization (mobilized) of phospholipase A2
1) Confidence 0.09 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2739214 Disease Relevance 0 Pain Relevance 0
Arachidonic acid is released from the phospholipid component of the cell membrane by the action of phospholipase A2.
Localization (released) of phospholipase A2
2) Confidence 0.04 Published 2008 Journal AAPS J Section Body Doc Link PMC2751374 Disease Relevance 1.08 Pain Relevance 0.27

General Comments

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