INT28194

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Context Info
Confidence 0.50
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Nppb) small molecule metabolic process (CYP2B6) extracellular region (Nppb)
endoplasmic reticulum (CYP2B6) nucleus (Nppb) cytoplasm (Nppb)
Anatomy Link Frequency
liver 1
Nppb (Rattus norvegicus)
CYP2B6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 17 99.60 Very High Very High Very High
alcohol 1 35.12 Quite Low
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Toxicity 1 50.68 Quite High
Necrosis 1 34.76 Quite Low
Hepatotoxicity 2 28.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of the other purified P450 isozymes examined, a beta-naphthoflavone (BNF)-inducible hamster liver P450 promoted APAP activation at rates even higher than those obtained with human P450IIE1.
BNF Positive_regulation (inducible) of P450 in liver associated with paracetamol
1) Confidence 0.50 Published 1989 Journal Arch. Biochem. Biophys. Section Abstract Doc Link 2729995 Disease Relevance 0.05 Pain Relevance 0.88

General Comments

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