INT281979

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.40
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (MDK) signal transduction (MDK) extracellular region (MDK)
MDK (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 144 99.32 Very High Very High Very High
corticosteroid 24 74.96 Quite High
Inflammation 6 71.20 Quite High
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 138 97.44 Very High Very High Very High
Targeted Disruption 9 95.76 Very High Very High Very High
INFLAMMATION 3 71.20 Quite High
Cancer 3 70.16 Quite High
Bronchopulmonary Dysplasia 27 5.00 Very Low Very Low Very Low
Hypoxia 3 5.00 Very Low Very Low Very Low
Emphysema 3 5.00 Very Low Very Low Very Low
Hyperglycemia 3 5.00 Very Low Very Low Very Low
Pneumonia 3 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Collectively, these data suggest that MK is normally decreased in late gestation, corresponding to increased GC and decreased RA signals.
Negative_regulation (decreased) of MK associated with rheumatoid arthritis
1) Confidence 0.21 Published 2009 Journal Respir Res Section Body Doc Link PMC2739515 Disease Relevance 0.71 Pain Relevance 0.10
Cells treated with hormones (DEX, cAMP, or DCI) had significantly decreased MK protein levels, with an apparent additive effect of GC and cAMP to repress the culture-induced increase in MK and RA eliminated the repressive effects of hormones (**p < 0.05 vs. no RA).
Negative_regulation (decreased) of MK associated with rheumatoid arthritis and dexamethasone
2) Confidence 0.21 Published 2009 Journal Respir Res Section Body Doc Link PMC2739515 Disease Relevance 0.42 Pain Relevance 0.17
A representative Western blot for MK is shown in Figure 3a with a histogram demonstrating densitometric analysis with normalization with ?
Negative_regulation (blot) of MK
3) Confidence 0.18 Published 2009 Journal Respir Res Section Body Doc Link PMC2739515 Disease Relevance 0.27 Pain Relevance 0.23

General Comments

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