INT282063

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Context Info
Confidence 0.09
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Prkca) endoplasmic reticulum (Prkca) enzyme binding (Prkca)
protein complex (Prkca) cytoplasm (Prkca) cytosol (Prkca)
Anatomy Link Frequency
nociceptors 2
Ngf (Mus musculus)
Prkca (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 8 100.00 Very High Very High Very High
Nerve growth factor 6 100.00 Very High Very High Very High
nociceptor 44 97.20 Very High Very High Very High
antagonist 3 72.76 Quite High
agonist 4 68.76 Quite High
low threshold mechanoreceptor 4 67.28 Quite High
Mechanotransduction 3 50.00 Quite Low
c fibre 19 42.44 Quite Low
Action potential 16 26.48 Quite Low
dorsal root ganglion 13 19.00 Low Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 34 67.60 Quite High
Injury 4 52.64 Quite High
Ganglion Cysts 13 19.00 Low Low
Nociception 6 18.84 Low Low
Hyperalgesia 6 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Arrhythmias 2 Under Development 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cesare and colleagues showed that NGF and activators of protein kinase C (PKC) can increase the density of mechanosensitive currents in the membrane of isolated nociceptors (Di Castro et al. 2006).
NGF Positive_regulation (increase) of Positive_regulation (activators) of PKC in nociceptors associated with kinase c, nerve growth factor and nociceptor
1) Confidence 0.09 Published 2009 Journal The Journal of Physiology Section Body Doc Link PMC2742277 Disease Relevance 0.18 Pain Relevance 0.80

General Comments

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