INT282065

Context Info Confidence 0.14 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.85 Pain Relevance 1.11

extracellular space (Calca, Ngf) extracellular region (Calca, Ngf) signal transduction (Ngf) nucleus (Calca) intracellular (Calca) cytoplasm (Calca)

Anatomy Link Frequency nerve 2 Calca (Mus musculus) Ngf (Mus musculus)

Pain Link Frequency Relevance Heat Nerve growth factor 12 100.00 Calcitonin gene-related peptide 2 100.00 nociceptor 88 98.20 Mechanotransduction 6 50.00 low threshold mechanoreceptor 8 42.64 c fibre 38 28.04 Action potential 32 26.24 dorsal root ganglion 26 6.56 Kinase C 16 5.00 Hyperalgesia 12 5.00

Disease Link Frequency Relevance Heat Rheumatoid Arthritis 68 94.68 Nociception 12 92.00 Ganglion Cysts 26 6.56 Hyperalgesia 12 5.00 INFLAMMATION 10 5.00 Injury 8 5.00 Pain 4 5.00 Dislocations 2 5.00 Arrhythmias 2 Under Development 2 5.00 Decapitation 2 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

One population expresses TrkA, the receptor for nerve growth factor (NGF), and calcitonin gene-related peptide (CGRP) and is thus often referred to as the population of peptidergic neurones.

calcitonin gene-related peptide Binding (receptor) of NGF in nerve associated with nerve growth factor and calcitonin gene-related peptide

1) Confidence 0.14 Published 2009 Journal The Journal of Physiology Section Body Doc Link PMC2742277 Disease Relevance 0.42 Pain Relevance 0.55

One population expresses TrkA, the receptor for nerve growth factor (NGF), and calcitonin gene-related peptide (CGRP) and is thus often referred to as the population of peptidergic neurones.

calcitonin gene-related peptide Binding (receptor) of nerve growth factor in nerve associated with nerve growth factor and calcitonin gene-related peptide

2) Confidence 0.14 Published 2009 Journal The Journal of Physiology Section Body Doc Link PMC2742277 Disease Relevance 0.42 Pain Relevance 0.55

General Comments

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