INT282121

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Context Info
Confidence 0.09
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ldha) mitochondrion (Ldha) oxidoreductase activity (Ldha)
carbohydrate metabolic process (Ldha) cytoplasm (Ldha)
Anatomy Link Frequency
lung 2
Ldha (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 9 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Weight Loss 10 98.98 Very High Very High Very High
Infection 40 97.96 Very High Very High Very High
Influenza Virus Infection 30 96.04 Very High Very High Very High
Shock 5 48.08 Quite Low
Bacterial Infection 3 39.48 Quite Low
Severe Acute Respiratory Syndrome 7 38.72 Quite Low
Coronavirus Infection 3 38.32 Quite Low
Autoimmune Disease 1 21.84 Low Low
Sprains And Strains 3 11.92 Low Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In mice treated 9x with the PCN, the protection against a subsequent primary influenza virus infection was characterized by a significantly greater reduction in viral burdens by day 7 post-infection (Figure 3A), and by the absence of any weight loss (Figure 3B), and lung damage, as indicated by the decreased levels of albumin (Figure 3C) and lactate dehydrogenase (LDH) (Figure 3D) recovered from the broncho-alveolar lavage fluid (BALF) [11], [12].
Negative_regulation (decreased) of Gene_expression (levels) of lactate dehydrogenase in lung associated with weight loss, influenza virus infection and infection
1) Confidence 0.09 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2743193 Disease Relevance 0.52 Pain Relevance 0

General Comments

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