INT282128

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Context Info
Confidence 0.37
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.12
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il10, Icam1) extracellular region (Il10) cell adhesion (Icam1)
plasma membrane (Icam1) intracellular (Il10)
Anatomy Link Frequency
sciatic nerve 3
Il10 (Mus musculus)
Icam1 (Mus musculus)
Pain Link Frequency Relevance Heat
Sciatic nerve 39 99.84 Very High Very High Very High
anesthesia 1 95.80 Very High Very High Very High
Demyelination 17 93.04 High High
Inflammation 17 5.00 Very Low Very Low Very Low
Spinal cord 16 5.00 Very Low Very Low Very Low
cytokine 15 5.00 Very Low Very Low Very Low
Neuritis 3 5.00 Very Low Very Low Very Low
Peripheral nervous system 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 28 98.12 Very High Very High Very High
Disease Progression 8 97.12 Very High Very High Very High
Demyelinating Disease 22 93.04 High High
Paralysis 34 92.80 High High
Disease 38 90.76 High High
Toxicity 4 40.08 Quite Low
INFLAMMATION 17 5.00 Very Low Very Low Very Low
Death 10 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 10 5.00 Very Low Very Low Very Low
Chronic Inflammatory Demyelinating Polyradiculoneuropathy 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
First, overexpression of IL-10 results in upregulation of ICAM-1 on sciatic nerve tissue.
Gene_expression (overexpression) of IL-10 in sciatic nerve Positive_regulation (results) of Positive_regulation (upregulation) of ICAM-1 in sciatic nerve associated with sciatic nerve
1) Confidence 0.37 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2743195 Disease Relevance 1.12 Pain Relevance 0.28

General Comments

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