INT282139

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grm1, Grip2) endoplasmic reticulum (Grip2) cytoskeleton (Grip2)
nucleus (Grm1) cytoplasm (Grip2) signal transducer activity (Grm1)
Grm1 (Rattus norvegicus)
Grip2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 26 100.00 Very High Very High Very High
Lasting pain 1 96.20 Very High Very High Very High
central pain 2 94.32 High High
Pain 2 83.44 Quite High
depression 2 78.16 Quite High
Dorsal horn 5 73.60 Quite High
Spinal cord 9 73.12 Quite High
medulla 13 57.92 Quite High
Thalamus 2 49.96 Quite Low
Kinase C 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 5 96.20 Very High Very High Very High
Nociception 7 84.52 Quite High
Depression 2 78.16 Quite High
Decapitation 1 38.56 Quite Low
Myelodysplastic Syndromes 2 5.00 Very Low Very Low Very Low
Ganglion Cysts 2 5.00 Very Low Very Low Very Low
Ketoacidosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, we provided strong evidences that the activation of group I mGluR subtypes, mGluR1 and mGluR5, and their signal transduction pathways, differentially regulates glutamate release and AMPA receptor-mediated synaptic responses in the Vo region.
mGluR1 Regulation (regulates) of AMPA receptor associated with glutamate
1) Confidence 0.00 Published 2009 Journal Mol Pain Section Body Doc Link PMC2743647 Disease Relevance 0.62 Pain Relevance 0.69

General Comments

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