INT282276

Context Info Confidence 0.16 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 1.16 Pain Relevance 0.31

nucleus (Tfdp1) cell cycle (Tfdp1) DNA binding (Tfdp1) transcription factor binding (Tfdp1)

Tfdp1 (Mus musculus)

Pain Link Frequency Relevance Heat metalloproteinase 2 71.64 Pain 8 59.84 Inflammation 28 59.12 cINOD 14 5.00 COX-2 inhibitor 12 5.00 aspirin 6 5.00 Inflammatory stimuli 4 5.00 corticosteroid 2 5.00 cytokine 2 5.00 Bile 2 5.00

Disease Link Frequency Relevance Heat Cancer 112 83.60 Colon Cancer 66 66.88 Pain 8 59.84 INFLAMMATION 34 59.12 Death 4 51.68 Apoptosis 16 49.60 Breast Cancer 6 17.04 Targeted Disruption 8 13.52 Intestinal Polyps 2 8.68 Intestinal Cancer 4 6.80

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Four of these receptor subtypes bind PGE2 (EP1-EP4), two bind PGD2 (DP1 and DP2), and the other receptors bind PGF2, PGI2, and TxA2 (FP, IP, and TP) respectively (Narumiya et al. 1999; Breyer et al. 2001; Hirai et al. 2001).

DP1 Binding (bind) of

1) Confidence 0.16 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2745153 Disease Relevance 0.58 Pain Relevance 0.15

Four of these receptor subtypes bind PGE2 (EP1-EP4), two bind PGD2 (DP1 and DP2), and the other receptors bind PGF2, PGI2, and TxA2 (FP, IP, and TP) respectively (Narumiya et al. 1999; Breyer et al. 2001; Hirai et al. 2001).

DP1 Binding (bind) of

2) Confidence 0.13 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2745153 Disease Relevance 0.58 Pain Relevance 0.15

General Comments

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