INT282285

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptger2) mitochondrion (Cpox) oxidoreductase activity (Cpox)
plasma membrane (Ptger2) signal transducer activity (Ptger2) cytoplasm (Cpox)
Anatomy Link Frequency
colon 2
Cpox (Mus musculus)
Ptger2 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 7 91.60 High High
Inflammation 14 82.32 Quite High
Pain 4 81.20 Quite High
COX-2 inhibitor 6 49.92 Quite Low
aspirin 3 43.52 Quite Low
corticosteroid 1 38.92 Quite Low
Inflammatory stimuli 2 7.68 Low Low
cytokine 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 56 99.84 Very High Very High Very High
Colon Cancer 33 97.56 Very High Very High Very High
INFLAMMATION 17 91.20 High High
Pain 4 81.20 Quite High
Fever 1 80.48 Quite High
Apoptosis 8 72.64 Quite High
Lung Cancer 2 67.84 Quite High
Retinoblastoma 1 37.48 Quite Low
Aberrant Crypt Foci 2 37.28 Quite Low
Malignant Neoplastic Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because COX-2 is responsible for the increased PGE2 production in cancer, the inhibition of COX-2 activity is critical for colon cancer chemoprevention.
COX Regulation (responsible) of Gene_expression (production) of PGE2 in colon associated with cancer and colon cancer
1) Confidence 0.00 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2745153 Disease Relevance 0.84 Pain Relevance 0.50

General Comments

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