INT282317

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.37
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 7
Disease Relevance 6.87
Pain Relevance 1.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Arc) plasma membrane (Arc) cytoskeleton (Arc)
cytoskeleton organization (Arc) cytoplasm (Arc)
Anatomy Link Frequency
neurons 6
gonadal 2
Arc (Mus musculus)
Pain Link Frequency Relevance Heat
Peripheral nerve injury 4 98.52 Very High Very High Very High
Neuropathic pain 16 97.32 Very High Very High Very High
Lasting pain 28 96.16 Very High Very High Very High
Acute pain 8 95.64 Very High Very High Very High
Pain 84 93.28 High High
IPN 16 92.88 High High
Dorsal horn neuron 24 88.88 High High
qutenza 20 82.04 Quite High
parabrachial 4 80.64 Quite High
Dorsal horn 48 80.20 Quite High
Disease Link Frequency Relevance Heat
Aids-related Complex 765 100.00 Very High Very High Very High
Nociception 164 100.00 Very High Very High Very High
Nervous System Injury 24 98.52 Very High Very High Very High
Neuropathic Pain 28 97.32 Very High Very High Very High
Pain 112 96.16 Very High Very High Very High
Inflammatory Pain 16 92.88 High High
Urological Neuroanatomy 4 78.96 Quite High
Hyperalgesia 12 63.68 Quite High
Targeted Disruption 136 58.76 Quite High
Depression 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Under conditions of high levels of circulating gonadal steroids, ARC Kiss1 expression decreases [10], thus ARC kisspeptin neurons are predicted to play a functional role in negative feedback regulation.
Negative_regulation (decreases) of Gene_expression (expression) of ARC in gonadal associated with aids-related complex
1) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912854 Disease Relevance 0.53 Pain Relevance 0
Temporal expression of Arc/Arg3.1 mRNA was highest at 1.5 hrs post injection and then gradually declined (Fig. 4C).
Negative_regulation (declined) of Gene_expression (expression) of Arc/Arg3.1 mRNA associated with aids-related complex
2) Confidence 0.34 Published 2010 Journal Mol Pain Section Body Doc Link PMC2920254 Disease Relevance 1.59 Pain Relevance 0.54
The number of Arc/Arg3.1 mRNA expressing neurons increased over time, reached a peak at 4 hours and then declined (Fig. 4B).
Negative_regulation (number) of Gene_expression (expressing) of Arc/Arg3.1 mRNA in neurons associated with aids-related complex
3) Confidence 0.34 Published 2010 Journal Mol Pain Section Body Doc Link PMC2920254 Disease Relevance 1.24 Pain Relevance 0.33
Expression of Arc/Arg3.1 mRNA following nociceptive stimulation occurs in a subset of c-Fos labeled neurons and is intensity dependent
Negative_regulation (occurs) of Gene_expression (Expression) of Arc/Arg3.1 mRNA in neurons associated with nociception and aids-related complex
4) Confidence 0.33 Published 2010 Journal Mol Pain Section Body Doc Link PMC2920254 Disease Relevance 1.00 Pain Relevance 0.22
The finding that only a small number of Arc/Arg3.1 positive neurons also expressed NK-1 or PKC-?
Negative_regulation (number) of Gene_expression (neurons) of Arc/Arg3.1 in neurons associated with aids-related complex
5) Confidence 0.33 Published 2010 Journal Mol Pain Section Body Doc Link PMC2920254 Disease Relevance 1.27 Pain Relevance 0.59
Rayleigh vector plots indicated that, unlike in the SCN, the phase of peak PER2::LUC expression in the Arc and DMH was significantly correlated with time of cull (p < 0.00001; see additional file 1: Fig.
Negative_regulation (phase) of Gene_expression (expression) of Arc associated with aids-related complex
6) Confidence 0.33 Published 2009 Journal Mol Brain Section Body Doc Link PMC2745382 Disease Relevance 0.61 Pain Relevance 0
Intact MBH slice cultures were initially imaged on the EM-CCD camera to confirm the location of PER2::LUC expression in the Arc, ME/PT and DMH, and then placed in PMTs.
Negative_regulation (location) of Gene_expression (expression) of Arc associated with aids-related complex
7) Confidence 0.33 Published 2009 Journal Mol Brain Section Body Doc Link PMC2745382 Disease Relevance 0.63 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox