INT282380

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.38
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.06
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Atg16l1) cytoplasm (Atg16l1)
Anatomy Link Frequency
plasma 1
Atg16l1 (Mus musculus)
Pain Link Frequency Relevance Heat
Crohn's disease 102 99.32 Very High Very High Very High
Inflammation 47 71.84 Quite High
potassium channel 1 43.12 Quite Low
Bile 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Clonidine 2 5.00 Very Low Very Low Very Low
Substantia nigra 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
carbamazepine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 154 99.32 Very High Very High Very High
Targeted Disruption 14 98.32 Very High Very High Very High
Inflammatory Bowel Disease 139 80.96 Quite High
Apoptosis 11 77.52 Quite High
INFLAMMATION 40 71.84 Quite High
Colitis 10 54.32 Quite High
Enteritis 1 52.00 Quite High
Familial Mediterranean Fever 2 50.00 Quite Low
Neurodegenerative Disease 32 35.84 Quite Low
Communicable Diseases 2 34.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, the autophagy genes IRGM and ATG16L1 have also been associated specifically to CD [42]–[43].
ATG16L1 Binding (associated) of associated with crohn's disease
1) Confidence 0.38 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2745755 Disease Relevance 1.18 Pain Relevance 0.39
Moreover, Cadwell et al. provided evidence that in ATG16L1 knockout mice, granule exocytosis is abnormal [67, 68], and recently it has been shown that recruitment of ATG16L1 to the site of bacterial entry in the plasma membrane is dependent on activation of NOD2 by bacteria ([69]).
ATG16L1 Binding (recruitment) of in plasma associated with targeted disruption
2) Confidence 0.16 Published 2010 Journal International Journal of Inflammation Section Body Doc Link PMC2992817 Disease Relevance 0.73 Pain Relevance 0.19
The Atg12–Atg5 conjugate interacts non-covalently with Atg16L, which oligomerizes to form an 800-kDa complex [8], which is necessary for autophagosome formation.
Atg16L Binding (oligomerizes) of
3) Confidence 0.12 Published 2010 Journal Seminars in Cell & Developmental Biology Section Body Doc Link PMC2938570 Disease Relevance 0.08 Pain Relevance 0
The Atg12–Atg5 conjugate interacts non-covalently with Atg16L, which oligomerizes to form an 800-kDa complex [8], which is necessary for autophagosome formation.
Atg16L Binding (interacts) of
4) Confidence 0.12 Published 2010 Journal Seminars in Cell & Developmental Biology Section Body Doc Link PMC2938570 Disease Relevance 0.08 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox