INT282406

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Context Info
Confidence 0.13
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.15
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
skeletal muscle 2
Hypism (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 38 97.64 Very High Very High Very High
cytokine 13 78.52 Quite High
chemokine 7 15.16 Low Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 40 100.00 Very High Very High Very High
Insulin Resistance 38 100.00 Very High Very High Very High
Hyperinsulinism 3 100.00 Very High Very High Very High
INFLAMMATION 42 97.64 Very High Very High Very High
Obesity 63 97.12 Very High Very High Very High
Hypertrophy 2 85.96 High High
Diabetes Mellitus 11 22.32 Low Low
Adhesions 3 20.44 Low Low
Atherosclerosis 3 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Two-week high fat feeding induced hyperinsulinemia and severe hepatic and skeletal muscle insulin resistance in WT but not 12/15LO KO mice. 12/15LO KO mice exhibited significantly greater insulin-stimulated skeletal muscle Akt phosphorylation after HFD, compared to WT mice, corresponding to their greater insulin sensitivity.
Positive_regulation (stimulated) of Positive_regulation (induced) of hyperinsulinemia in skeletal muscle associated with targeted disruption, hyperinsulinism and insulin resistance
1) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746280 Disease Relevance 2.15 Pain Relevance 0.28

General Comments

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