INT282421

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.48
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mapk8, Ins1) mitochondrion (Mapk8) carbohydrate metabolic process (Ins1)
cytosol (Mapk8) signal transduction (Mapk8) extracellular space (Ins1)
Anatomy Link Frequency
Adipose tissue 1
Mapk8 (Mus musculus)
Ins1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 13 100.00 Very High Very High Very High
Inflammation 38 99.28 Very High Very High Very High
chemokine 7 5.00 Very Low Very Low Very Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 38 99.82 Very High Very High Very High
INFLAMMATION 42 99.28 Very High Very High Very High
Obesity 63 99.02 Very High Very High Very High
Diabetes Mellitus 11 96.88 Very High Very High Very High
Hypertrophy 2 80.48 Quite High
Hyperinsulinism 3 76.32 Quite High
Aging 1 75.60 Quite High
Body Weight 2 66.96 Quite High
Dyslipidemia /

Combined Dyslipidemia

1 53.52 Quite High
Hypoxia 1 46.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Adipose tissue inflammation induces insulin resistance through inactivation of insulin receptor substrates (IRS) by cytokine-activated JNK, IKK?
JNK Negative_regulation (inactivation) of insulin in Adipose tissue associated with inflammation, obesity, insulin resistance and cytokine
1) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746280 Disease Relevance 2.43 Pain Relevance 0.31

General Comments

This test has worked.

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