INT282449

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Context Info
Confidence 0.11
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Erbb3) extracellular space (Erbb3) nucleus (Erbb3)
kinase activity (Erbb3)
Erbb3 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 14 15.92 Low Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
positron emission tomography 3 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Peripheral nerve injury 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 1 90.52 High High
Breast Cancer 10 89.68 High High
Leukemia 1 80.00 Quite High
Cancer 80 74.84 Quite High
Carcinoma 8 71.84 Quite High
Prostate Cancer 4 68.72 Quite High
Severe Combined Immunodeficiency 2 60.96 Quite High
Adhesions 22 60.88 Quite High
Stomach Cancer 1 58.84 Quite High
Adenocarcinoma 4 52.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
4 can regulate the expression of ErBB-3 at the level of protein translation, resulting in a significant induction of ErBB-2/ErBB-3 heterodimerization and consequent activation of PI3K (Folgiero et al. 2007; Liu et al. 2007).
Regulation (regulate) of Positive_regulation (induction) of ErBB-3
1) Confidence 0.11 Published 2008 Journal Perspectives in Medicinal Chemistry Section Body Doc Link PMC2746574 Disease Relevance 0.91 Pain Relevance 0

General Comments

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