INT2825

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Context Info
Confidence 0.23
First Reported 1979
Last Reported 2002
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.30
Pain Relevance 1.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ptger3) signal transducer activity (Ptger3)
Anatomy Link Frequency
trigeminal nerve 2
urine 2
Ptger3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 10 100.00 Very High Very High Very High
fifth nerve 1 98.66 Very High Very High Very High
antagonist 4 98.00 Very High Very High Very High
aspirin 4 88.76 High High
diclofenac 1 86.36 High High
Potency 1 78.72 Quite High
Inflammation 1 75.00 Quite High
Calcitonin gene-related peptide 1 49.68 Quite Low
Migraine 1 34.64 Quite Low
ischemia 1 33.92 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 82.12 Quite High
Headache 1 34.64 Quite Low
Cv Unclassified Under Development 1 33.92 Quite Low
Acidosis 1 32.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Release of PGE and F fron non-inflamed synovial membrane was not influenced by hydrocortisone in vivo and in vitro.
Neg (not) Regulation (influenced) of Localization (Release) of PGE
1) Confidence 0.23 Published 1979 Journal Nippon Yakurigaku Zasshi Section Abstract Doc Link 544394 Disease Relevance 0.23 Pain Relevance 0.28
Effects of NSAID on the excretion of PGE and PG main urinary metabolite (PGMUM) in rat urine were determined.
Regulation (Effects) of Localization (excretion) of PGE in urine associated with cinod
2) Confidence 0.10 Published 1980 Journal Nippon Yakurigaku Zasshi Section Abstract Doc Link 6781993 Disease Relevance 0.07 Pain Relevance 0.78
The present results provide evidence that ATP has poor, if at all, direct excitatory effects on CGRP-containing trigeminal nerve endings in the isolated dura and its facilitatory action seems to depend on G-protein coupled P2Y receptors and secondary PGE(2) release.
Regulation (depend) of Localization (release) of PGE in trigeminal nerve associated with fifth nerve
3) Confidence 0.03 Published 2002 Journal Pain Section Abstract Doc Link 12044622 Disease Relevance 0 Pain Relevance 0.23

General Comments

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