INT282501

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Cyp19a1) oxidoreductase activity (Cyp19a1) endoplasmic reticulum (Cyp19a1)
cytoplasm (Cyp19a1)
Cyp19a1 (Mus musculus)
Aaiq4 (Mus musculus)
Pain Link Frequency Relevance Heat
sSRI 34 92.28 High High
Dopamine 5 82.52 Quite High
cocaine 1 77.84 Quite High
Catechol-O-methyltransferase 7 66.00 Quite High
addiction 2 45.76 Quite Low
Glutamate 17 5.00 Very Low Very Low Very Low
nMDA receptor 13 5.00 Very Low Very Low Very Low
Serotonin 11 5.00 Very Low Very Low Very Low
Neurotransmitter 7 5.00 Very Low Very Low Very Low
behavioral therapy 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 5 100.00 Very High Very High Very High
Anxiety Disorder 209 87.28 High High
Congenital Anomalies 7 86.52 High High
Tourette's Syndrome 9 47.32 Quite Low
Attention Deficit Hyperactivity Disorder 9 46.80 Quite Low
Drug Dependence 1 45.76 Quite Low
Manic Depressive Disorder 3 44.72 Quite Low
Urological Neuroanatomy 1 44.64 Quite Low
Obsessive-compulsive Disorder 12 5.00 Very Low Very Low Very Low
Cognitive Disorder 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hill et al. [114] eliminated aromatase expression by targeted disruption of the Cyp19 gene, thereby producing estrogen deficient mice (designated ArKO mice).
Negative_regulation (disruption) of Cyp19 Negative_regulation (eliminated) of Gene_expression (expression) of aromatase associated with targeted disruption
1) Confidence 0.01 Published 2008 Journal Current Chemical Genomics Section Body Doc Link PMC2746669 Disease Relevance 0.60 Pain Relevance 0.27

General Comments

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