INT282506

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.32
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.26
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Comt) methyltransferase activity (Comt) plasma membrane (Comt)
Anatomy Link Frequency
hypothalamus 4
ocd (Mus musculus)
Comt (Mus musculus)
Pain Link Frequency Relevance Heat
Catechol-O-methyltransferase 14 100.00 Very High Very High Very High
Dopamine 10 95.12 Very High Very High Very High
sSRI 68 76.64 Quite High
cocaine 2 62.20 Quite High
addiction 4 30.12 Quite Low
Glutamate 34 5.00 Very Low Very Low Very Low
nMDA receptor 26 5.00 Very Low Very Low Very Low
Serotonin 22 5.00 Very Low Very Low Very Low
Neurotransmitter 14 5.00 Very Low Very Low Very Low
behavioral therapy 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 418 100.00 Very High Very High Very High
Targeted Disruption 10 86.52 High High
Urological Neuroanatomy 2 82.32 Quite High
Congenital Anomalies 14 70.88 Quite High
Tourette's Syndrome 18 31.68 Quite Low
Attention Deficit Hyperactivity Disorder 18 31.16 Quite Low
Drug Dependence 2 30.12 Quite Low
Manic Depressive Disorder 6 29.08 Quite Low
Obsessive-compulsive Disorder 24 5.00 Very Low Very Low Very Low
Cognitive Disorder 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The OCD-like behaviors of male ArKO mice are suggested to be caused by dysregulation of estrogen-induced catechol-O-methyltransferase (COMT) expression in the hypothalamus.
OCD Positive_regulation (induced) of Gene_expression (expression) of catechol-O-methyltransferase in hypothalamus associated with catechol-o-methyltransferase and anxiety disorder
1) Confidence 0.32 Published 2008 Journal Current Chemical Genomics Section Body Doc Link PMC2746669 Disease Relevance 0.63 Pain Relevance 0.42
The OCD-like behaviors of male ArKO mice are suggested to be caused by dysregulation of estrogen-induced catechol-O-methyltransferase (COMT) expression in the hypothalamus.
OCD Positive_regulation (induced) of Gene_expression (expression) of COMT in hypothalamus associated with catechol-o-methyltransferase and anxiety disorder
2) Confidence 0.32 Published 2008 Journal Current Chemical Genomics Section Body Doc Link PMC2746669 Disease Relevance 0.63 Pain Relevance 0.42

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox