INT282558

Context Info Confidence 0.16 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.26 Pain Relevance 0

nucleoplasm (POU5F1, MAPK1) DNA binding (POU5F1, MAPK1) cytoplasm (POU5F1, MAPK1) cytosol (POU5F1, MAPK1) nucleus (POU5F1, MAPK1) transcription factor binding (POU5F1, MAPK1)

POU5F1 (Homo sapiens) MAPK1 (Homo sapiens)

Pain Link Frequency Relevance Heat Potency 4 9.12 tetrodotoxin 3 5.00 Action potential 3 5.00 Sciatic nerve 3 5.00 Hippocampus 2 5.00 anesthesia 1 5.00 withdrawal 1 5.00

Disease Link Frequency Relevance Heat Stress 3 97.32 Chromosome Aberrations 1 75.96 Obesity 4 50.00 Brain Injury 3 21.60 Apoptosis 7 10.88 Death 4 8.04 Targeted Disruption 2 5.00 Disease 2 5.00 Teratoma 2 5.00 Adhesions 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Our recent study indicated that exogenic Oct4 can activate MEK and ERK1/2 following the induction of de-differentiation.

Oct4 Positive_regulation (activate) of ERK1/2

1) Confidence 0.16 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2747014 Disease Relevance 0.26 Pain Relevance 0

General Comments

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