INT282594

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Context Info
Confidence 0.18
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.89
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (WNT5A) extracellular space (WNT5A) extracellular region (WNT5A)
proteinaceous extracellular matrix (WNT5A) plasma membrane (WNT5A) embryo development (WNT5A)
WNT5A (Homo sapiens)
Pain Link Frequency Relevance Heat
Action potential 3 69.76 Quite High
cytokine 6 69.60 Quite High
imagery 5 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
Sciatic nerve 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Choroideremia 166 97.80 Very High Very High Very High
Muscular Dystrophy 2 88.96 High High
Adhesions 4 85.72 High High
Obesity 4 75.00 Quite High
Stress 8 32.16 Quite Low
Disease 12 5.00 Very Low Very Low Very Low
Apoptosis 7 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, expression levels of genes encoding secreted proteins from different functional groups including CFI, CC2, NRG1, MMP7, WNT5A, RSOPO2, CSF3R, DPP4, IL1 were deregulated altered in CHM cells compared to the control.
Localization (secreted) of WNT5A associated with choroideremia
1) Confidence 0.18 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2793004 Disease Relevance 0.76 Pain Relevance 0.06
The negatively regulated genes included FAS, TNFR, COL6A1, JAM2, FOXQ1, FOXO1, NESTIN, SMAD3, SLIT3, DKK1, WNT5A, BMP1, and GLIS3 which are implicated in differentiation processes as well as a number of novel genes.
Localization (implicated) of WNT5A
2) Confidence 0.10 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2747014 Disease Relevance 0.13 Pain Relevance 0.03

General Comments

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