INT282664

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Aif1, Gfap) cytosol (Aif1) structural molecule activity (Gfap)
plasma membrane (Aif1) cytoskeleton (Aif1) extracellular matrix organization (Gfap)
Aif1 (Mus musculus)
Gfap (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 8 97.10 Very High Very High Very High
vanilloid receptor subtype 1 2 95.28 Very High Very High Very High
Calcitonin gene-related peptide 16 93.46 High High
Spinal cord 44 78.12 Quite High
Sciatic nerve 56 36.04 Quite Low
isoflurane 6 33.04 Quite Low
intrathecal 56 5.00 Very Low Very Low Very Low
Pain 28 5.00 Very Low Very Low Very Low
Lasting pain 22 5.00 Very Low Very Low Very Low
Neuropathic pain 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 54 50.00 Quite Low
Injury 4 44.40 Quite Low
Nervous System Injury 22 32.16 Quite Low
Congenital Anomalies 2 14.60 Low Low
Pain 52 5.00 Very Low Very Low Very Low
Cold Sores 20 5.00 Very Low Very Low Very Low
Neuropathic Pain 18 5.00 Very Low Very Low Very Low
Sprains And Strains 10 5.00 Very Low Very Low Very Low
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Herpes Simplex Virus 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-calcitonin gene-related peptide (CGRP, 1:5000, Peninsula Laboratories, San Carlos, CA), rabbit anti-vanilloid receptor subtype 1 (TRPV1; 1:200; gift from GlaxoSmithKline, Middlesex, United Kingdom), rat anti-Substance P (1:400, BD Bioscience, Basel, Switzerland), mouse anti-neurofilament 200 (NF200, 1:500, Sigma, Basel, Switzerland), rabbit anti-ionized calcium binding adaptor molecule 1 (Iba1, 1:200, Wako Pure Chemical Industries, Osaka, Japan) and rabbit anti-glial fibrillary acidic protein (GFAP, 1:1000, DakoCytomation, Glostrup, Denmark).
Iba1 Binding (binding) of GFAP associated with vanilloid receptor subtype 1, substance p and calcitonin gene-related peptide
1) Confidence 0.06 Published 2009 Journal Mol Pain Section Body Doc Link PMC2747840 Disease Relevance 0 Pain Relevance 0.34
-calcitonin gene-related peptide (CGRP, 1:5000, Peninsula Laboratories, San Carlos, CA), rabbit anti-vanilloid receptor subtype 1 (TRPV1; 1:200; gift from GlaxoSmithKline, Middlesex, United Kingdom), rat anti-Substance P (1:400, BD Bioscience, Basel, Switzerland), mouse anti-neurofilament 200 (NF200, 1:500, Sigma, Basel, Switzerland), rabbit anti-ionized calcium binding adaptor molecule 1 (Iba1, 1:200, Wako Pure Chemical Industries, Osaka, Japan) and rabbit anti-glial fibrillary acidic protein (GFAP, 1:1000, DakoCytomation, Glostrup, Denmark).
Iba1 Binding (binding) of fibrillary acidic protein associated with vanilloid receptor subtype 1, substance p and calcitonin gene-related peptide
2) Confidence 0.05 Published 2009 Journal Mol Pain Section Body Doc Link PMC2747840 Disease Relevance 0 Pain Relevance 0.34

General Comments

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