INT282809

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (YWHAZ) mitochondrion (YWHAZ) protein complex (YWHAZ)
cytoplasm (YWHAZ) cytosol (YWHAZ) signal transduction (YWHAZ)
YWHAZ (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 50 99.38 Very High Very High Very High
corticosteroid 3 98.78 Very High Very High Very High
cINOD 28 87.84 High High
cOX1 1 78.88 Quite High
COX2 2 78.24 Quite High
cytokine 1 59.44 Quite High
ischemia 1 37.44 Quite Low
diclofenac 45 5.00 Very Low Very Low Very Low
acular 41 5.00 Very Low Very Low Very Low
alcohol 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 43 99.38 Very High Very High Very High
Increased Venous Pressure Under Development 3 92.96 High High
Miosis 8 91.64 High High
Ocular Hypertension 8 87.24 High High
Injury 6 46.80 Quite Low
Autoimmune Disease 1 40.04 Quite Low
Hypersensitivity 1 38.76 Quite Low
Cv Unclassified Under Development 1 37.44 Quite Low
Cataract 13 12.08 Low Low
Infection 1 9.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Corticosteroids, the potent anti-inflammatory agents elicit their action by blocking the enzyme phospholipase A2 to inhibit arachidonic acid production, thereby preventing the synthesis of all the PGs, thromboxanes and eicosanoids.
Negative_regulation (blocking) of Positive_regulation (enzyme) of phospholipase A2 associated with corticosteroid and inflammation
1) Confidence 0.03 Published 2008 Journal AAPS J Section Body Doc Link PMC2751374 Disease Relevance 1.07 Pain Relevance 0.52

General Comments

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