INT282821

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.06
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TACR1, P2RX7) cytoplasm (TACR1, P2RX7) signal transducer activity (TACR1)
TACR1 (Homo sapiens)
P2RX7 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 8 100.00 Very High Very High Very High
substance P 4 100.00 Very High Very High Very High
chemokine 4 71.92 Quite High
cytokine 2 71.12 Quite High
Neurobehavioral 2 50.16 Quite High
Pain management 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 6 94.20 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 24 93.92 High High
Mental Disorders 2 74.16 Quite High
Communicable Diseases 2 72.36 Quite High
Hypersensitivity 2 71.44 Quite High
Immunodeficiency 2 60.24 Quite High
Disease 10 5.00 Very Low Very Low Very Low
Vomiting 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ability of neurokinin-1 receptor (NK-1R) antagonists to target the substance P receptor demonstrating antiviral and immunomodulatory effects (16–18) represents a new therapeutic target with the potential to interrupt a pathway critical to HIV replication (19,20).
neurokinin-1 receptor Regulation (target) of P receptor associated with antagonist, acquired immune deficiency syndrome or hiv infection and substance p
1) Confidence 0.01 Published 2008 Journal AAPS J Section Body Doc Link PMC2751447 Disease Relevance 1.03 Pain Relevance 0.27
The ability of neurokinin-1 receptor (NK-1R) antagonists to target the substance P receptor demonstrating antiviral and immunomodulatory effects (16–18) represents a new therapeutic target with the potential to interrupt a pathway critical to HIV replication (19,20).
NK-1R Regulation (target) of P receptor associated with antagonist, acquired immune deficiency syndrome or hiv infection and substance p
2) Confidence 0.01 Published 2008 Journal AAPS J Section Body Doc Link PMC2751447 Disease Relevance 1.02 Pain Relevance 0.27

General Comments

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