INT282856

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.18
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Aggf1) extracellular region (Aggf1) cell adhesion (Aggf1)
intracellular (Aggf1) cytoplasm (Aggf1)
Anatomy Link Frequency
corneas 1
neutrophil 1
Aggf1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 44 100.00 Very High Very High Very High
metalloproteinase 5 92.68 High High
cytokine 7 84.88 Quite High
chemokine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 45 100.00 Very High Very High Very High
Disease 9 96.60 Very High Very High Very High
Necrosis 2 95.40 Very High Very High Very High
Cancer 5 95.04 Very High Very High Very High
Corneal Neovascularization 45 84.96 Quite High
Edema 1 79.60 Quite High
Burns 11 54.12 Quite High
Chemical Burns 6 37.16 Quite Low
Wound Healing 5 18.72 Low Low
Corneal Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The extent of upregulation of other detected S100A genes and pro-inflammatory or pro-angiogenic genes was also decreased by neutrophil depletion.
Positive_regulation (upregulation) of pro-angiogenic in neutrophil associated with inflammation
1) Confidence 0.02 Published 2010 Journal Molecular Vision Section Abstract Doc Link PMC2994359 Disease Relevance 0.49 Pain Relevance 0.23
were significantly repressed in PSP-treated corneas compared to control corneas whereas the anti-angiogenic factor, PEDF, was upregulated in PSP-treated corneas when compared to the control corneas (Figure 5).
Positive_regulation (upregulated) of anti-angiogenic factor in corneas
2) Confidence 0.02 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2751803 Disease Relevance 0.69 Pain Relevance 0.22

General Comments

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