INT282866

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Context Info
Confidence 0.11
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.14
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bpifa2, VEGFA) lipid binding (Bpifa2) extracellular space (VEGFA)
growth (VEGFA) proteinaceous extracellular matrix (VEGFA) cytoplasm (VEGFA)
Anatomy Link Frequency
PSP 2
Bpifa2 (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 19 80.40 Quite High
Inflammatory response 1 53.00 Quite High
metalloproteinase 5 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Corneal Neovascularization 39 96.48 Very High Very High Very High
Burns 10 83.52 Quite High
INFLAMMATION 20 80.40 Quite High
Eye Disease 1 65.52 Quite High
Disease 3 51.48 Quite High
Corneal Disease 3 39.88 Quite Low
Pathologic Neovascularization 1 39.08 Quite Low
Wound Healing 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As shown in Figure 5, PSP suppressed the expression of VEGF, MMP2, and MMP9 and stimulated the expression of PEDF, suggesting that PSP may inhibit CNV by downregulating the expression of angiogenic factors and upregulating the expression of the anti-angiogenic factor.
PSP Negative_regulation (suppressed) of Gene_expression (expression) of VEGF in PSP associated with corneal neovascularization
1) Confidence 0.11 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2751803 Disease Relevance 1.14 Pain Relevance 0.19

General Comments

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