INT28291

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Context Info
Confidence 0.11
First Reported 1981
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.50
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tshr) signal transducer activity (Tshr)
Anatomy Link Frequency
plasma 1
thyroid 1
Tshr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 1 98.40 Very High Very High Very High
Pain 7 92.60 High High
Inflammation 27 60.16 Quite High
cytokine 22 44.28 Quite Low
Calcitonin gene-related peptide 17 33.60 Quite Low
substance P 16 33.24 Quite Low
antagonist 39 5.00 Very Low Very Low Very Low
Nerve growth factor 28 5.00 Very Low Very Low Very Low
agonist 22 5.00 Very Low Very Low Very Low
gABA 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 96.32 Very High Very High Very High
Stress 48 95.60 Very High Very High Very High
Hyperthyroidism 4 93.84 High High
Pain 2 91.84 High High
Thyroid Disease 6 90.04 High High
Thyroiditis 2 83.16 Quite High
INFLAMMATION 28 60.16 Quite High
Infection 1 54.96 Quite High
Cancer 22 53.52 Quite High
Ganglion Cysts 1 21.60 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The TtT/GF cell line indeed expresses mRNA of GH-R, TSH-R and ACTH-R, but not of LH-R, FSH-R and PRL-R (739).
Gene_expression (expresses) of TSH-R
1) Confidence 0.11 Published 2008 Journal Journal of Neuroendocrinology Section Body Doc Link PMC2229370 Disease Relevance 0.64 Pain Relevance 0.03
Diencephalic structures that influence plasma thyrotropin (TSH) in male rats under pentobarbital anesthesia (35 mg/kg, IP) were studied by combining medial preoptic area-suprachiasmatic nucleus (MPOA-Sch) bilateral electrical stimulation (monophasic pulses, 200 microA at 50 Hz, 30 min) with progressive midline lesions produced by a retractable Halász knife.
Gene_expression (influence) of thyrotropin in plasma associated with anesthesia and urological neuroanatomy
2) Confidence 0.06 Published 1981 Journal Brain Res. Bull. Section Abstract Doc Link 7225903 Disease Relevance 0.10 Pain Relevance 0.10
Thyrotropin-binding inhibiting IgG and antibody to thyroid microsomal antigen were both positive.
Gene_expression (positive) of Thyrotropin-binding in thyroid
3) Confidence 0.06 Published 1989 Journal Eur. J. Pediatr. Section Abstract Doc Link 2744032 Disease Relevance 0.77 Pain Relevance 0.52

General Comments

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