INT282916

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Context Info
Confidence 0.45
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.47
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MUC1) plasma membrane (MUC1) nucleus (MUC1)
cytoplasm (MUC1)
Anatomy Link Frequency
epithelial cells 2
MUC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nicotine 9 99.50 Very High Very High Very High
antagonist 4 94.08 High High
gABA 59 92.24 High High
GABAergic 46 90.12 High High
agonist 2 53.36 Quite High
Glutamate 7 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
peptic ulcer disease 4 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metaplasia 5 93.28 High High
Hyperplasia 2 82.24 Quite High
Sprains And Strains 26 64.16 Quite High
Generalized Anxiety Disorder 5 60.84 Quite High
Nicotine Addiction 68 59.36 Quite High
Alagille Syndrome 1 53.24 Quite High
Infection 29 50.00 Quite Low
Gastritis 10 50.00 Quite Low
Stress 4 42.20 Quite Low
Adenocarcinoma 5 38.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, MUC1 mRNA levels increased progressively in culture but were not significantly affected by the presence of H. pylori (Figure 5B).
Neg (not) Positive_regulation (increased) of Transcription (levels) of MUC1
1) Confidence 0.45 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2752161 Disease Relevance 0.12 Pain Relevance 0
Fu et al [41] showed that incubation of rhesus macaque bronchial epithelial cells with nicotine for 48 hr significantly increased mucin mRNA levels.
Positive_regulation (increased) of Transcription (levels) of mucin in epithelial cells associated with nicotine
2) Confidence 0.04 Published 2010 Journal Respir Res Section Body Doc Link PMC2988726 Disease Relevance 0.35 Pain Relevance 0.79

General Comments

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