INT283009

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bcl2, Pdss2) cytoplasm (Bcl2, Pdss2) cell morphogenesis (Bcl2)
endoplasmic reticulum (Bcl2) intracellular (Bcl2) cell proliferation (Bcl2)
Anatomy Link Frequency
groove 1
Bcl2 (Mus musculus)
Pdss2 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 104 94.68 High High
Viral Infection 13 72.00 Quite High
Infection 51 63.28 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 50.00 Quite Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Starvation 3 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the Beclin1 peptide (KD 40 nM) binds to vBcl-2 with a much higher affinity than is observed for the Bak (KD 76 nM) and Bax peptides (KD 690 nM) [28], raising the possibility that Beclin1 may not necessarily share binding sites with the pro-apoptotic Bcl-2 family members for the hydrophobic groove of vBcl-2.
vBcl-2 Binding (binds) of KD in groove associated with apoptosis
1) Confidence 0.03 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2752191 Disease Relevance 0.56 Pain Relevance 0

General Comments

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