INT283061

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ERCC8) transport (LDLR) small molecule metabolic process (LDLR)
plasma membrane (LDLR) nucleus (ERCC8) protein complex (ERCC8)
Anatomy Link Frequency
blood 1
ERCC8 (Homo sapiens)
LDLR (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 22 100.00 Very High Very High Very High
Nephrotoxicity 1 87.28 High High
Increased Venous Pressure Under Development 1 83.00 Quite High
Recurrence 105 50.40 Quite High
Disease 54 50.00 Quite Low
Lymphoproliferative Disease 1 7.76 Low Low
Cytomegalovirus Infection 1 5.36 Low Low
Chronic Renal Failure 29 5.00 Very Low Very Low Very Low
Renal Disease 29 5.00 Very Low Very Low Very Low
Hemolytic Uremic Syndrome 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The rationale behind maintaining high CsA blood concentration is to overcome the effect of high serum levels of low-density lipoprotein (LDL) (secondary to recurrent NS), which binds CsA and is further responsible for low levels of free available CsA.
CsA Binding (binds) of low-density lipoprotein in blood associated with disorder of lipid metabolism
1) Confidence 0.00 Published 2009 Journal Pediatr Nephrol Section Body Doc Link PMC2753770 Disease Relevance 0.44 Pain Relevance 0

General Comments

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