INT283101

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Context Info
Confidence 0.57
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.96
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Dag1) extracellular space (Dag1) extracellular region (Dag1)
plasma membrane (Dag1) cytoskeleton (Dag1) nucleus (Dag1)
Dag1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 4 43.68 Quite Low
gABA 2 42.52 Quite Low
Glutamate 2 42.16 Quite Low
ischemia 4 28.80 Quite Low
potassium channel 12 20.48 Low Low
adenocard 10 5.00 Very Low Very Low Very Low
Inflammatory mediators 10 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retina Disease 50 99.20 Very High Very High Very High
Pressure And Volume Under Development 40 89.80 High High
Injury 6 80.68 Quite High
Gliosis 14 53.60 Quite High
Diabetic Retinopathy 8 53.20 Quite High
Disease 4 52.04 Quite High
Retinal Vein Occlusion 2 31.12 Quite Low
Cv Unclassified Under Development 4 28.80 Quite Low
Death 2 18.64 Low Low
INFLAMMATION 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that experimental retinal detachment causes alterations in water transport and impairments in fluid absorption of Müller cells, associated with a downregulation of Dp71 expression.
Negative_regulation (downregulation) of Gene_expression (expression) of Dp71 associated with retina disease
1) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2754330 Disease Relevance 0.65 Pain Relevance 0
Summarizing these results, both gene and protein expression of Dp71 are strongly reduced after experimental retinal detachment in C57BL/6 mice.
Negative_regulation (reduced) of Gene_expression (expression) of Dp71 associated with retina disease
2) Confidence 0.41 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2754330 Disease Relevance 0.30 Pain Relevance 0

General Comments

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