INT283194

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Context Info
Confidence 0.13
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.59
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Vamp8) vesicle-mediated transport (Vamp8) protein complex assembly (Vamp8)
Anatomy Link Frequency
muscle 5
Vamp8 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 5 99.10 Very High Very High Very High
beta blocker 5 86.44 High High
depression 5 13.68 Low Low
Pain 5 12.80 Low Low
agonist 5 5.00 Very Low Very Low Very Low
fibrosis 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 99.10 Very High Very High Very High
Staphylococcus Infection 5 88.20 High High
Muscular Dystrophy 215 84.16 Quite High
Toxicity 5 47.80 Quite Low
Depression 10 41.28 Quite Low
Anxiety Disorder 5 40.68 Quite Low
Stress 10 25.40 Quite Low
Affective Disorder 5 13.68 Low Low
Pain 5 12.80 Low Low
Duchenne Muscular Dystrophy 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Light microscopy and immunocytochemistry done masked to treatment showed no differences in inflammatory infiltrates between the treated and control EDB muscles in all patients (table 2).
Gene_expression (muscles) of EDB in muscles associated with inflammation
1) Confidence 0.13 Published 2009 Journal Lancet Neurol Section Body Doc Link PMC2755039 Disease Relevance 0.27 Pain Relevance 0.09
For all patients, an open biopsy of both EDB muscles was done between 3 and 4 weeks after injection.
Gene_expression (muscles) of EDB in muscles
2) Confidence 0.13 Published 2009 Journal Lancet Neurol Section Body Doc Link PMC2755039 Disease Relevance 0.06 Pain Relevance 0
All patients showed some short-lived, bilateral, localised reactions in both EDB muscles after the injections and muscle biopsies (table 2).
Gene_expression (muscles) of EDB in muscle
3) Confidence 0.13 Published 2009 Journal Lancet Neurol Section Body Doc Link PMC2755039 Disease Relevance 0.21 Pain Relevance 0.07
L normal saline (0ยท9%) and were injected in one EDB muscle; the contralateral EDB muscle was injected with 900 ?
Gene_expression (muscle) of EDB in muscle
4) Confidence 0.13 Published 2009 Journal Lancet Neurol Section Body Doc Link PMC2755039 Disease Relevance 0 Pain Relevance 0
However, in patients one and two, who received low-dose AVI-4658, there was no clear difference in protein expression between the treated and control EDB muscle biopsies (webappendix).
Gene_expression (expression) of EDB in muscle
5) Confidence 0.12 Published 2009 Journal Lancet Neurol Section Body Doc Link PMC2755039 Disease Relevance 0.05 Pain Relevance 0

General Comments

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