INT283365

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Context Info
Confidence 0.50
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (APC) chromosome organization (APC) cell adhesion (APC)
plasma membrane (APC) cytoskeleton (APC) nucleus (APC)
APC (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 2 18.00 Low Low
fibrosis 6 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 104 100.00 Very High Very High Very High
Cancer 48 88.56 High High
Hepatocellular Cancer 51 71.28 Quite High
Liver Cancer 10 61.44 Quite High
Hepatitis B Virus Infection 3 40.24 Quite Low
Hepatitis C Virus Infection 2 9.60 Low Low
Metastasis 11 5.00 Very Low Very Low Very Low
Cirrhosis 9 5.00 Very Low Very Low Very Low
Fibrosis 4 5.00 Very Low Very Low Very Low
Hepatitis Virus Infection 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The truncated or functionally inactive APC protein which can result from (1) transcriptional silencing through promoter methylation, (2) a point mutation of the APC gene or (3) loss of heterozygosity (LOH) (Hiltunen et al. 1997; Chen et al. 2005) loses the ability to interact with ?
Positive_regulation (result) of APC gene Binding (mutation) of associated with familial adenomatous polyposis
1) Confidence 0.50 Published 2007 Journal J Cancer Res Clin Oncol Section Body Doc Link PMC2757596 Disease Relevance 1.43 Pain Relevance 0

General Comments

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