INT283428

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.09
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Lcn2) transport (Lcn2) extracellular space (Lcn2)
extracellular region (Lcn2) plasma membrane (Nt5e) cytoplasm (Nt5e)
Lcn2 (Mus musculus)
Nt5e (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 48 88.72 High High
chemokine 24 77.64 Quite High
Inflammatory response 18 62.24 Quite High
anesthesia 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pneumonia 33 98.96 Very High Very High Very High
Iron Overload 3 89.92 High High
INFLAMMATION 66 88.72 High High
Sepsis 9 86.72 High High
Sprains And Strains 48 82.08 Quite High
Infection 24 74.48 Quite High
Bacterial Meningitis 3 48.96 Quite Low
Lower Respiratory Tract Infection 3 37.32 Quite Low
Hemophilus Infection 3 25.84 Quite Low
Suicidal Behaviour 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lcn2 is able to bind both ferric and aferric Ent, thereby depleting Ent from the microenvironment and inhibiting bacterial uptake of Ent-bound iron.
Negative_regulation (depleting) of Lcn2 Binding (bind) of Ent
1) Confidence 0.06 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2757716 Disease Relevance 0.38 Pain Relevance 0
Lcn2 is able to bind both ferric and aferric Ent, thereby depleting Ent from the microenvironment and inhibiting bacterial uptake of Ent-bound iron.
Negative_regulation (inhibiting) of Lcn2 Binding (bind) of Ent
2) Confidence 0.06 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2757716 Disease Relevance 0.40 Pain Relevance 0
If Fe is not depleted during colonization, then Lcn2 may bind primarily Fe-Ent.
Neg (not) Negative_regulation (depleted) of Lcn2 Binding (bind) of Ent
3) Confidence 0.05 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2757716 Disease Relevance 0.31 Pain Relevance 0.15

General Comments

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