INT283459

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Context Info
Confidence 0.73
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Nup210) nuclear envelope (Nup210) endoplasmic reticulum (Nup210)
nucleus (Nup210)
Anatomy Link Frequency
rims 1
Nup210 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 2 83.52 Quite High
Bile 67 73.72 Quite High
fibrosis 14 41.44 Quite Low
Inflammation 23 18.88 Low Low
pruritus 14 5.00 Very Low Very Low Very Low
tolerance 14 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Biliary Liver Cirrhosis 246 97.20 Very High Very High Very High
Extrahepatic Cholestasis 1 71.76 Quite High
Autoimmune Disease 30 68.36 Quite High
Lymphadenopathy 1 60.16 Quite High
Fibrosis 16 41.44 Quite Low
Liver Disease 23 38.72 Quite Low
Chronic Hepatitis 1 36.88 Quite Low
Gallstones 23 36.32 Quite Low
Primary Sclerosing Cholangitis 5 21.44 Low Low
INFLAMMATION 23 18.88 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, specific ANA directed against nuclear body or envelope proteins such as anti-Sp100, presenting as multiple (6–12) nuclear dots at indirect immunofluorescence staining and anti-gp210, presenting as perinuclear rims have shown a specificity of >95% for PBC, although their sensitivity is low.
Localization (presenting) of gp210 in rims associated with biliary liver cirrhosis
1) Confidence 0.73 Published 2009 Journal Semin Immunopathol Section Body Doc Link PMC2758170 Disease Relevance 0.73 Pain Relevance 0.08

General Comments

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