INT283461

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL2) extracellular region (IL2) cell adhesion (IL2)
plasma membrane (SLC4A2) transmembrane transport (SLC4A2) cell-cell signaling (IL2)
IL2 (Homo sapiens)
SLC4A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 2 24.76 Low Low
Bile 67 5.00 Very Low Very Low Very Low
Inflammation 23 5.00 Very Low Very Low Very Low
fibrosis 14 5.00 Very Low Very Low Very Low
pruritus 14 5.00 Very Low Very Low Very Low
tolerance 14 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Biliary Liver Cirrhosis 246 97.64 Very High Very High Very High
Autoimmune Disease 30 49.08 Quite Low
Gallstones 23 48.16 Quite Low
Rhinitis 1 43.72 Quite Low
Granuloma 5 43.04 Quite Low
Disease 39 36.88 Quite Low
Disease Progression 8 33.92 Quite Low
Liver Disease 23 30.72 Quite Low
INFLAMMATION 23 24.40 Low Low
Targeted Disruption 3 17.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
II or IL-2 receptor or the AE2, gives rise to histologic and serologic changes mimicking PBC in different animal models and may be contributing to susceptibility for PBC in human.
IL-2 Binding (receptor) of AE2 associated with biliary liver cirrhosis
1) Confidence 0.01 Published 2009 Journal Semin Immunopathol Section Body Doc Link PMC2758170 Disease Relevance 0.98 Pain Relevance 0

General Comments

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