INT283503

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Context Info
Confidence 0.09
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.39
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC4A2) transmembrane transport (SLC4A2)
Anatomy Link Frequency
hepatocytes 2
AE-1 1
AE-2 1
SLC4A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 134 71.28 Quite High
methotrexate 8 62.80 Quite High
vincristine 6 57.68 Quite High
Pain 2 45.60 Quite Low
Inflammation 46 5.00 Very Low Very Low Very Low
fibrosis 28 5.00 Very Low Very Low Very Low
pruritus 28 5.00 Very Low Very Low Very Low
tolerance 28 5.00 Very Low Very Low Very Low
agonist 10 5.00 Very Low Very Low Very Low
corticosteroid 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease Progression 16 100.00 Very High Very High Very High
Cancer 46 95.84 Very High Very High Very High
Reprotox - General 1 76 91.76 High High
Malignant Neoplastic Disease 16 90.40 High High
Endometrial Cancer 12 87.28 High High
Biliary Liver Cirrhosis 492 85.68 High High
Necrosis 10 77.84 Quite High
Metastasis 6 76.84 Quite High
Gallstones 46 75.32 Quite High
Disease 80 57.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Most interestingly, a strong association with disease progression was also shown for AE2 rs 2303932 (T/A), a gene encoding for the apical anion exchanger 2 (AE2) in cholangiocytes and hepatocytes.
AE2 Binding (association) of in hepatocytes associated with disease progression
1) Confidence 0.09 Published 2009 Journal Semin Immunopathol Section Body Doc Link PMC2758170 Disease Relevance 1.04 Pain Relevance 0.04
Most interestingly, a strong association with disease progression was also shown for AE2 rs 2303932 (T/A), a gene encoding for the apical anion exchanger 2 (AE2) in cholangiocytes and hepatocytes.
AE2 Binding (association) of in hepatocytes associated with disease progression
2) Confidence 0.09 Published 2009 Journal Semin Immunopathol Section Body Doc Link PMC2758170 Disease Relevance 1.02 Pain Relevance 0.04
-hCG) (Figure 3) and cytokeratins (AE-1, AE-2) and negative for octamer binding transcription factor (OCT)-3/4, ?
AE-2 Binding (binding) of in AE-2
3) Confidence 0.05 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC3002375 Disease Relevance 0.66 Pain Relevance 0.06
-hCG) (Figure 3) and cytokeratins (AE-1, AE-2) and negative for octamer binding transcription factor (OCT)-3/4, ?
AE-2 Binding (binding) of in AE-1
4) Confidence 0.02 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC3002375 Disease Relevance 0.66 Pain Relevance 0.06

General Comments

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