INT283512

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Context Info
Confidence 0.11
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (CTLA4) plasma membrane (CTLA4)
CTLA4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 67 67.44 Quite High
Inflammation 23 5.00 Very Low Very Low Very Low
fibrosis 14 5.00 Very Low Very Low Very Low
pruritus 14 5.00 Very Low Very Low Very Low
tolerance 14 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
halothane 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Biliary Liver Cirrhosis 246 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 4 97.64 Very High Very High Very High
Diabetes Mellitus 1 96.32 Very High Very High Very High
Autoimmune Disease 30 94.96 High High
Necrosis 3 87.04 High High
Cancer 4 86.68 High High
Gallstones 23 59.92 Quite High
Disease 39 28.92 Quite Low
Disease Progression 8 14.48 Low Low
Apoptosis 27 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although an association of CTLA-4 variants and susceptibility to PBC could not be demonstrated in all studies [110, 111], Poupon et al. [112] most recently confirmed a potential role of TNF?
Neg (not) Positive_regulation (demonstrated) of CTLA-4 Binding (association) of associated with biliary liver cirrhosis
1) Confidence 0.11 Published 2009 Journal Semin Immunopathol Section Body Doc Link PMC2758170 Disease Relevance 1.03 Pain Relevance 0.03

General Comments

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