INT283518

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Context Info
Confidence 0.16
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.87
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC4A2) transmembrane transport (SLC4A2)
SLC4A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 134 98.96 Very High Very High Very High
corticosteroid 8 92.00 High High
Kinase C 2 75.12 Quite High
Inflammation 46 32.24 Quite Low
fibrosis 28 31.68 Quite Low
pruritus 28 5.00 Very Low Very Low Very Low
tolerance 28 5.00 Very Low Very Low Very Low
agonist 10 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Biliary Liver Cirrhosis 492 99.96 Very High Very High Very High
Increased Venous Pressure Under Development 4 95.80 Very High Very High Very High
Gallstones 46 84.40 Quite High
Disease 78 52.52 Quite High
Injury 18 36.00 Quite Low
INFLAMMATION 46 32.24 Quite Low
Fibrosis 32 31.68 Quite Low
Osteoporosis 22 28.88 Quite Low
Apoptosis 54 28.80 Quite Low
Cirrhosis 32 12.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AE2 expression and biliary bicarbonate secretion is usually diminished in PBC [241].
Negative_regulation (diminished) of Gene_expression (expression) of AE2 associated with biliary liver cirrhosis
1) Confidence 0.16 Published 2009 Journal Semin Immunopathol Section Body Doc Link PMC2758170 Disease Relevance 0.46 Pain Relevance 0.15
In PBC, expression of the hepatic AE2 and biliary bicarbonate secretion by AE2 are impaired [240, 241].
Negative_regulation (impaired) of Gene_expression (expression) of AE2 associated with biliary liver cirrhosis
2) Confidence 0.10 Published 2009 Journal Semin Immunopathol Section Body Doc Link PMC2758170 Disease Relevance 0.41 Pain Relevance 0.32

General Comments

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