INT283542

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.69
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Setx) nucleus (Setx) helicase activity (Setx)
molecular_function (Setx) cytoplasm (Setx)
Anatomy Link Frequency
lateral 2
SPG19 (Homo sapiens)
Setx (Mus musculus)
Pain Link Frequency Relevance Heat
Action potential 16 5.00 Very Low Very Low Very Low
carpal tunnel syndrome 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 16 100.00 Very High Very High Very High
Paraplegia 4 100.00 Very High Very High Very High
Motor Neuron Diseases 4 100.00 Very High Very High Very High
Frailty 26 98.68 Very High Very High Very High
Spastic Paraparesis 4 97.88 Very High Very High Very High
Syndrome 10 96.16 Very High Very High Very High
Ataxia 4 93.04 High High
Neurodegenerative Disease 2 89.60 High High
Lipodystrophy 2 86.68 High High
Hereditary Spastic Paraplegia 2 80.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The senataxin gene (SETX), primary associated with autosomal dominant juvenile amyotrophic lateral sclerosis (ALS4) and spastic paraplegia without neuropathy (SPG19), has now also been associated with distal HMN with pyramidal features [3, 8].
SPG19 Binding (associated) of SETX in lateral associated with paraplegia, neuropathic pain and motor neuron diseases
1) Confidence 0.06 Published 2009 Journal Neurogenetics Section Body Doc Link PMC2758216 Disease Relevance 1.84 Pain Relevance 0
The senataxin gene (SETX), primary associated with autosomal dominant juvenile amyotrophic lateral sclerosis (ALS4) and spastic paraplegia without neuropathy (SPG19), has now also been associated with distal HMN with pyramidal features [3, 8].
SPG19 Binding (associated) of senataxin in lateral associated with paraplegia, neuropathic pain and motor neuron diseases
2) Confidence 0.06 Published 2009 Journal Neurogenetics Section Body Doc Link PMC2758216 Disease Relevance 1.85 Pain Relevance 0

General Comments

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