INT28356

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Context Info
Confidence 0.06
First Reported 1988
Last Reported 1989
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.17
Pain Relevance 2.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

generation of precursor metabolites and energy (NRF1) mitochondrion organization (NRF1) nucleus (NRF1)
DNA binding (NRF1) cytoplasm (NRF1)
Anatomy Link Frequency
respiratory 3
NRF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opiate 5 99.72 Very High Very High Very High
qutenza 21 99.62 Very High Very High Very High
bradykinin 6 98.62 Very High Very High Very High
Hyperalgesia 1 83.04 Quite High
Codeine 3 75.12 Quite High
Inflammatory mediators 1 75.00 Quite High
Morphine 2 73.52 Quite High
anesthesia 2 56.48 Quite High
lidocaine 2 53.36 Quite High
narcan 1 31.04 Quite Low
Disease Link Frequency Relevance Heat
Cough 16 99.90 Very High Very High Very High
Hyperalgesia 1 83.04 Quite High
INFLAMMATION 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have therefore investigated the effect of prostaglandin E2 (PGE2), bradykinin (BK), histamine (H), and citric acid (C) on capsaicin-induced cough and increase in respiratory resistance (Rrs).
Spec (investigated) Positive_regulation (increase) of respiratory resistance in respiratory associated with qutenza, cough and bradykinin
1) Confidence 0.06 Published 1989 Journal Am. Rev. Respir. Dis. Section Abstract Doc Link 2751160 Disease Relevance 0.84 Pain Relevance 0.85
To determine the site of action of opiates in humans, we have studied the effect of systemic and inhaled opiates on cough and increase in respiratory resistance (Rrs) caused by inhaled capsaicin.
Positive_regulation (increase) of respiratory resistance in respiratory associated with qutenza, cough and opiate
2) Confidence 0.04 Published 1988 Journal J. Appl. Physiol. Section Abstract Doc Link 3182481 Disease Relevance 0.34 Pain Relevance 0.89
After inhalation of leukotriene D4 (LTD4), respiratory resistance (Rrs) increased by 115 +/- 11% (SE).
Positive_regulation (increased) of respiratory resistance in respiratory
3) Confidence 0.03 Published 1988 Journal J. Appl. Physiol. Section Abstract Doc Link 2968970 Disease Relevance 0 Pain Relevance 0.34

General Comments

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