INT283562

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp2) extracellular space (Mmp2) extracellular region (Mmp2)
proteinaceous extracellular matrix (Mmp2) plasma membrane (Mmp2) nucleus (Mmp2)
Anatomy Link Frequency
smooth muscle cell 3
basement membrane 1
Mmp2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neointima 18 97.12 Very High Very High Very High
Adhesions 26 72.40 Quite High
Hyperplasia 4 9.28 Low Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Vasculitis 6 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Cardiovascular Disease 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Vascular Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We demonstrated previously that active extracellular proteolysis is present in the process of arteriogenesis, which includes increased expression of MMP-2 and -9, degradation of the basement membrane and smooth muscle cell migration resulting in neointima formation [2].
Positive_regulation (increased) of Protein_catabolism (degradation) of MMP-2 in smooth muscle cell associated with neointima
1) Confidence 0.05 Published 2008 Journal Mol Cell Biochem Section Body Doc Link PMC2758386 Disease Relevance 0.17 Pain Relevance 0
We demonstrated previously that active extracellular proteolysis is present in the process of arteriogenesis, which includes increased expression of MMP-2 and -9, degradation of the basement membrane and smooth muscle cell migration resulting in neointima formation [2].
Positive_regulation (increased) of in basement membrane Protein_catabolism (degradation) of MMP-2 in smooth muscle cell associated with neointima
2) Confidence 0.02 Published 2008 Journal Mol Cell Biochem Section Body Doc Link PMC2758386 Disease Relevance 0.17 Pain Relevance 0

General Comments

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