INT283606

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Context Info
Confidence 0.44
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.13
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Gphn) plasma membrane (Gphn) cytoskeleton (Gphn)
intracellular (Gphn) cytoplasm (Gphn)
Gphn (Mus musculus)
Pain Link Frequency Relevance Heat
tetrodotoxin 2 9.08 Low Low
antagonist 14 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Glutamate receptor 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 14 66.16 Quite High
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Neurologic Manifestations 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When the same experiments were performed using overexpression of the NLS-tagged intrabodies, a dramatic change in gephyrin distribution was observed (Fig. 2b).
Regulation (change) of gephyrin
1) Confidence 0.44 Published 2007 Journal J Mol Neurosci Section Body Doc Link PMC2758390 Disease Relevance 0 Pain Relevance 0
First, both intrabodies immunoprecipitate gephyrin upon their co-expression in HEK 293 cells.
Regulation (immunoprecipitate) of gephyrin
2) Confidence 0.32 Published 2007 Journal J Mol Neurosci Section Body Doc Link PMC2758390 Disease Relevance 0.13 Pain Relevance 0

General Comments

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