INT283733

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Trib3, Creb1) mitochondrion (Creb1) nucleolus (Trib3)
DNA binding (Creb1) enzyme binding (Trib3) transcription factor binding (Creb1)
Anatomy Link Frequency
nucleus 1
Trib3 (Rattus norvegicus)
Creb1 (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 29 94.88 High High
Hippocampus 8 32.88 Quite Low
Pain 3 5.00 Very Low Very Low Very Low
nMDA receptor 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Thalamus 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
spinal dorsal horn 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 17 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Fever 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Hypercalcemia 1 5.00 Very Low Very Low Very Low
Dementia 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consequently, cAMP activates cAMP-dependent protein kinase (PKA), which may in turn activate cAMP response element binding protein (CREB), a transcription factor, in the nucleus.
kinase Positive_regulation (activate) of CREB in nucleus
1) Confidence 0.00 Published 2007 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2759147 Disease Relevance 0 Pain Relevance 0.28

General Comments

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