INT283743

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.12
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptger2) nucleus (Rtcd1) plasma membrane (Ptger2)
molecular_function (Rtcd1) ligase activity (Rtcd1) signal transducer activity (Ptger2)
Ptger2 (Mus musculus)
Rtcd1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 1 89.56 High High
midbrain 1 82.92 Quite High
Thalamus 2 82.52 Quite High
Hippocampus 8 82.12 Quite High
cerebral cortex 1 81.60 Quite High
long-term potentiation 29 68.48 Quite High
Pain 3 5.00 Very Low Very Low Very Low
nMDA receptor 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
spinal dorsal horn 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fever 3 62.80 Quite High
Targeted Disruption 17 19.36 Low Low
Stress 1 7.68 Low Low
Pain 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Hypercalcemia 1 5.00 Very Low Very Low Very Low
Dementia 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activation of EP1 elevates the levels of intracellular inositol phosphate and Ca2+ (Watabe et al. 1993), whereas the activation of EP2 or EP4 stimulates adenylate cyclase, resulting in increased levels of intracellular cAMP (Jumblatt and Paterson, 1991).
Positive_regulation (activation) of EP2 Positive_regulation (stimulates) of cyclase
1) Confidence 0.00 Published 2007 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2759147 Disease Relevance 0.12 Pain Relevance 0.27

General Comments

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