INT283842

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.35
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

kinase activity (Insrr)
Anatomy Link Frequency
central nervous system 2
hb (Mus musculus)
Insrr (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 6 99.52 Very High Very High Very High
cytokine 6 81.40 Quite High
monoamine 26 78.04 Quite High
Hippocampus 14 78.00 Quite High
Neurobehavioral 4 73.60 Quite High
depression 6 61.76 Quite High
Pyramidal cell 6 43.32 Quite Low
nMDA receptor 8 27.36 Quite Low
Eae 24 5.00 Very Low Very Low Very Low
Dopamine 22 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 4 93.44 High High
Schizophrenia 26 90.28 High High
Targeted Disruption 220 85.20 High High
Congenital Anomalies 18 77.00 Quite High
Depression 6 61.76 Quite High
Manic Depressive Disorder 4 60.92 Quite High
Mental Disorders 8 45.20 Quite Low
Neurodegenerative Disease 2 38.76 Quite Low
Cognitive Disorder 24 21.76 Low Low
Attention Deficit Hyperactivity Disorder 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and HB-EGF) are expressed at much higher levels than EGF itself [11], HB-EGF itself could be serving as a major physiologic ligand for EGF receptor within the central nervous system.
HB-EGF Binding (ligand) of receptor in central nervous system associated with central nervous system
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2759290 Disease Relevance 0.45 Pain Relevance 0.15
and HB-EGF) are expressed at much higher levels than EGF itself [11], it is possible that HB-EGF serves as a major physiologic ligand for the EGF receptor within the central nervous system.
HB-EGF Binding (ligand) of receptor in central nervous system associated with central nervous system
2) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2759290 Disease Relevance 0.90 Pain Relevance 0.23

General Comments

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