INT283865

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK1) transport (APOA5) mitochondrion (MAPK1)
DNA binding (MAPK1) microtubule organizing center (MAPK1) lipid binding (APOA5)
Anatomy Link Frequency
uterine smooth muscle 1
MAPK1 (Homo sapiens)
APOA5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Mechanotransduction 8 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Dismenorea 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 94 99.60 Very High Very High Very High
Pre-term Labor 12 5.00 Very Low Very Low Very Low
Polyhydramnios 6 5.00 Very Low Very Low Very Low
Dysmenorrhea 4 5.00 Very Low Very Low Very Low
Hypertension 4 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Colon Cancer 2 5.00 Very Low Very Low Very Low
Endometriosis (extended) 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In order to test the hypothesis that SmAV acts as a scaffolding protein to recruit ERK in focal adhesion signaling, stretched and unstretched uterine smooth muscle homogenates were immunoprecipitated (IP) with an anti-ERK antibody.
ERK Binding (recruit) of SmAV in uterine smooth muscle associated with adhesions
1) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2759504 Disease Relevance 0.22 Pain Relevance 0
Myometrial SmAV associates with tyrosine-phosphorylated proteins and ERK in a stretch-dependent manner
ERK Binding (associates) of SmAV
2) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2759504 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

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