INT284048

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.37
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Vtcn1) cellular_component (Vtcn1)
Cia1 (Mus musculus)
Vtcn1 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 87 100.00 Very High Very High Very High
rheumatoid arthritis 75 94.84 High High
Inflammation 24 61.68 Quite High
chemokine 2 56.16 Quite High
cytokine 5 54.68 Quite High
agonist 8 54.24 Quite High
Inflammatory response 4 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Freund adjuvant 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 84 100.00 Very High Very High Very High
Disease 33 95.20 Very High Very High Very High
Rheumatoid Arthritis 77 94.84 High High
Disease Progression 7 83.68 Quite High
Autoimmune Disease 18 66.08 Quite High
INFLAMMATION 28 61.68 Quite High
Cancer 3 59.28 Quite High
Experimental Arthritis 1 45.24 Quite Low
Lyme Disease 1 44.44 Quite Low
Immunization 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, our findings in the CIA mouse model support a critical role for B7-H4 as a checkpoint molecule and provide a possible explanation for the pathogenesis and progression in a significant fraction of patients with RA.
CIA Binding (findings) of B7-H4 associated with rheumatoid arthritis and arthritis
1) Confidence 0.02 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2760136 Disease Relevance 1.37 Pain Relevance 0.60

General Comments

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