INT284065

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Context Info
Confidence 0.53
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.02
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Reg3g)
Anatomy Link Frequency
goblet cell 1
Reg3g (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 14 100.00 Very High Very High Very High
metalloproteinase 1 93.16 High High
methotrexate 1 82.40 Quite High
Crohn's disease 1 40.48 Quite Low
cytokine 7 5.00 Very Low Very Low Very Low
fibrosis 7 5.00 Very Low Very Low Very Low
Thoracotomy 6 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 19 100.00 Very High Very High Very High
Fibrosis 17 100.00 Very High Very High Very High
Hyperplasia 2 98.26 Very High Very High Very High
Cancer 51 92.48 High High
Pancreatic Cancer 32 81.04 Quite High
Metastasis 4 64.52 Quite High
Stomach Cancer 2 60.32 Quite High
Congenital Anomalies 4 52.56 Quite High
Disease 6 46.64 Quite Low
Colon Cancer 1 44.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Contrary to reg1A, reg1B, reg3A and reg3G genes, all located on chromosome 2p12, reg4 is on chromosome 1p13.1-p12.
Gene_expression (is) of reg3G
1) Confidence 0.53 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2760775 Disease Relevance 0.59 Pain Relevance 0.04
Interestingly, genes relating to goblet cell hyperplasia and mucous production are also up-regulated (Clca3, Agr2, Slc26a4), with differential expression of other genes associated with inflammatory, fibrotic or immune responses (up-regulation of Reg3g, Ear11, Retnla, Nappa, and Ccr9; down-regulation of Arg1, CD5L and Alox15).
Gene_expression (expression) of Reg3g in goblet cell associated with fibrosis, inflammation and hyperplasia
2) Confidence 0.45 Published 2009 Journal Respir Res Section Body Doc Link PMC2770038 Disease Relevance 0.43 Pain Relevance 0.13

General Comments

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