INT284089

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Context Info
Confidence 0.27
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (NTRK2, SERPINE1) endosome (NTRK2) extracellular space (SERPINE1)
extracellular region (SERPINE1)
NTRK2 (Homo sapiens)
SERPINE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
bDMF 21 100.00 Very High Very High Very High
depression 1 60.60 Quite High
long-term potentiation 1 55.00 Quite High
Migraine 1 41.76 Quite Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 126 95.32 Very High Very High Very High
Death 1 83.76 Quite High
Diabetes Mellitus 15 63.68 Quite High
Depression 1 60.60 Quite High
Cardiovascular Disease 33 46.88 Quite Low
Headache 1 41.76 Quite Low
Aging 11 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 6 5.00 Very Low Very Low Very Low
Stroke 4 5.00 Very Low Very Low Very Low
Hypoxia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, due to an increased level of PAI-1, mature BDNF could not be produced, which in turn could not bind to TrkB.
TrkB Neg (not) Binding (bind) of PAI-1 associated with bdmf
1) Confidence 0.27 Published 2008 Journal Genome Biol Section Body Doc Link PMC2760875 Disease Relevance 0.73 Pain Relevance 0.61

General Comments

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