INT284109

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Context Info
Confidence 0.47
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (GTF3C1) nucleus (GTF3C1) DNA binding (GTF3C1)
GTF3C1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 1 89.80 High High
bDMF 21 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
long-term potentiation 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 126 83.24 Quite High
Cardiovascular Disease 33 67.24 Quite High
Diabetes Mellitus 15 57.04 Quite High
Disorder Of Lipid Metabolism 1 26.04 Quite Low
Aging 11 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 6 5.00 Very Low Very Low Very Low
Stroke 4 5.00 Very Low Very Low Very Low
Hypoxia 3 5.00 Very Low Very Low Very Low
Hypoglycemia 2 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The hub genes included those encoding general transcription factor iiic, polypeptide 1, alpha 220 kda (GTF3C1), which is involved in RNA polymerase III-mediated transcription, microtubule-associated protein 4 (MAP4), which promotes microtubule stability and affects cell growth [28], and proprotein convertase subtilisin/kexin type 2 (PC2), which is responsible for the processing of neuropeptide precursors.
Positive_regulation (involved) of GTF3C1 associated with neuropeptide
1) Confidence 0.47 Published 2008 Journal Genome Biol Section Body Doc Link PMC2760875 Disease Relevance 0.76 Pain Relevance 0.04

General Comments

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